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Fig. 3 | Journal of Biomedical Science

Fig. 3

From: Imaging extracellular vesicles: current and emerging methods

Fig. 3

Strategies for EV labeling and imaging. Labeling EV with fluorescent dye or fluorescent protein can be imaged by fluorescent microscopy. EVs expressing bioluminescence proteins can be imaged by ultra-sensitive CCD. EVs incorporated with USPIO can be used for MRI imaging. EVs label with isotopes can be used for nuclear imaging. CFDA-SE: carboxyfluorescein diacetate succinimidyl ester; calcein AM: calcein acetoxymethyl; USPIO: ultra-small super paramagnetic iron oxide; 99mTc-HMPAO: 99mTc-hexamethylpropylene-amineoxime; CCD: charge-coupled device

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