Fig. 3From: Imaging extracellular vesicles: current and emerging methodsStrategies for EV labeling and imaging. Labeling EV with fluorescent dye or fluorescent protein can be imaged by fluorescent microscopy. EVs expressing bioluminescence proteins can be imaged by ultra-sensitive CCD. EVs incorporated with USPIO can be used for MRI imaging. EVs label with isotopes can be used for nuclear imaging. CFDA-SE: carboxyfluorescein diacetate succinimidyl ester; calcein AM: calcein acetoxymethyl; USPIO: ultra-small super paramagnetic iron oxide; 99mTc-HMPAO: 99mTc-hexamethylpropylene-amineoxime; CCD: charge-coupled deviceBack to article page