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Table 2 The comparison of the GC risk as H. pylori bearing with different HtrA-L171 and CagL-Y58/E59 status

From: H. pylori isolates with amino acid sequence polymorphisms as presence of both HtrA-L171 & CagL-Y58/E59 increase the risk of gastric cancer

HtrA-L171

CagL-Y58/E59

NUD n (%)

GC n (%)

P value

OR (95% CI)

-

-

27 (49.1)

2 (13.3)

0.013

6.3 (1.3–30.4)

-

+

28 (50.9)

13 (86.7)

-

-

27 (81.8)

2 (25.0)

0.002

13.5 (2.2–84.0)

+

-

6 (18.2)

6 (75.0)

-

-

27 (79.4)

2 (20.0)

< 0.001

15.4 (2.7–89.5)

+

+

7 (20.6)

8 (80.0)

  1. Abbreviations: NUD non-ulcer dyspepsia, GC gastric cancer, OR odds ratio, 95% CI 95% confidence interval. The P value was determined by χ2 test
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Journal of Biomedical Science

ISSN: 1423-0127