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Table 2 The comparison of the GC risk as H. pylori bearing with different HtrA-L171 and CagL-Y58/E59 status

From: H. pylori isolates with amino acid sequence polymorphisms as presence of both HtrA-L171 & CagL-Y58/E59 increase the risk of gastric cancer

HtrA-L171 CagL-Y58/E59 NUD n (%) GC n (%) P value OR (95% CI)
- - 27 (49.1) 2 (13.3) 0.013 6.3 (1.3–30.4)
- + 28 (50.9) 13 (86.7)
- - 27 (81.8) 2 (25.0) 0.002 13.5 (2.2–84.0)
+ - 6 (18.2) 6 (75.0)
- - 27 (79.4) 2 (20.0) < 0.001 15.4 (2.7–89.5)
+ + 7 (20.6) 8 (80.0)
  1. Abbreviations: NUD non-ulcer dyspepsia, GC gastric cancer, OR odds ratio, 95% CI 95% confidence interval. The P value was determined by χ2 test