Skip to main content

Table 3 The comparison of histopathology among NUD subjects with different status of HtrA-L171 & CagL-Y58/E59 of H. pylori infection

From: H. pylori isolates with amino acid sequence polymorphisms as presence of both HtrA-L171 & CagL-Y58/E59 increase the risk of gastric cancer

Histology score, mean (SD)

HtrA-L171 & CagL-Y58/E59 status

P value

Both absence (n = 27)

HtrA-171 L alone (n = 28)

CagL-Y58/E59 alone (n = 6)

Both presence (n = 7)

Antrum

 AIS

1.44 (0.97)

1.64 (0.78)

1.33 (1.03)

1.29 (0.95)

NS

 CIS

2.74 (0.53)

2.96 (0.19)

2.67 (0.82)

2.71 (0.49)

0.039a; 0.037b

 HPD

3.26 (1.26)

3.36 (1.19)

3.17 (1.72)

3.86 (1.07)

NS

Corpus

 AIS

1.00 (0.96)

0.93 (0.98)

1.17 (0.98)

0.57 (0.98)

NS

 CIS

2.37 (0.79)

2.32 (0.82)

2.83 (0.41)

2.14 (0.07)

NS

 HPD

3.41 (1.37)

3.46 (1.17)

3.67 (1.03)

2.43 (1.62)

NS

  1. Abbreviations: AIS acute inflammation score (range 0–3), CIS chronic inflammation score (range 1–3); HPD, H. pylori density (range 0–5). Statistical analysis was performed by Mann-Whitney U test. a indicated significance with P < 0.05 of such parameter between both absence and HtrA-L171 alone H. pylori infection; b between HtrA-L171 alone and both presence. NS: no significant difference
Back to article page

Journal of Biomedical Science

ISSN: 1423-0127