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Fig. 5 | Journal of Biomedical Science

Fig. 5

From: SOX17 overexpression sensitizes chemoradiation response in esophageal cancer by transcriptional down-regulation of DNA repair and damage response genes

Fig. 5

Increased expression of DNA repair and DNA damage response genes in ESCC radio-resistant cell line. a RT-qPCR showed that KYSE510 radio-resistant cells (KYSE510R) exhibited significantly higher basal expression levels of DNA repair genes (upper) and DNA damage response genes (lower) in comparison with KYSE510 parental cells. Data represent mean ± S.D. P-values were determined by two-tailed Student’s t-test. *P < 0.05; **P < 0.01. b The protein expression level of DNA repair proteins and DNA damage response proteins in KYSE510-R was higher than that in KYSE510 cells. β-actin was used as an internal control for western blots

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