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Table 1 Expression levels of let-7d and miR-205 depending on the clinicopathological parameters in HNSCC patients; T-test, p < 0.05 was considered significant

From: Low let-7d and high miR-205 expression levels positively influence HNSCC patient outcome

Parameter Group Cases analyzed let-7d miR-205  
Mean ± SEM p-val Mean ± SEM p-val
Age < 61.3 159 7.621 ± 0.04545 0.3846 13.49 ± 0.08659 0.8371
> 61.3 147 7.564 ± 0.04723 13.51 ± 0.08951
Gender Female 95 7.537 ± 0.06120 0.2445 13.59 ± 0.09850 0.621
Male 221 7.619 ± 0.03845 13.46 ± 0.07811
Alcohol Yes 206 7.650 ± 0.03906 0.0227 13.5 ± 0.07550 0.5678
No 97 7.491 ± 0.05784 13.5 ± 0.1092
Grade G1 + G2 219 7.515 ± 0.03841 0.0002 13.48 ± 0.06774 0.5185
G3 + G4 80 7.796 ± 0.06118 13.57 ± 0.1461
Cancer Stage I + II 74 7.554 ± 0.06325 0.6672 13.52 ± 0.1002 0.3658
III + IV 197 7.587 ± 0.04059 13.39 ± 0.08370
T Stage T1 + T2 118 7.555 ± 0.05406 0.4987 13.42 ± 0.08618 0.5219
T3 + T4 154 7.602 ± 0.04398 13.44 ± 0.09825
N Stage N0 154 7.531 ± 0.04499 0.0729 13.55 ± 0.07323 0.3485
N1 + N2 + N3 140 7.651 ± 0.04992 13.41 ± 0.1054
Perineural Invasion Yes 105 7.555 ± 0.05409 0.5565 13.27 ± 0.1050 0.0165
No 110 7.601 ± 0.05588 13.62 ± 0.1045
Angiolymphatic Invasion Yes 67 7.762 ± 0.05671 0.0024 13.15 ± 0.1663 0.008
No 139 7.506 ± 0.05074 13.59 ± 0.07981
Disease Surgical Margin Status Negative 210 7.550 ± 0.03765 0.5931 13.45 ± 0.07263 0.1907
Positive 30 7.607 ± 0.09610 13.23 ± 0.1742
Lymph Node Neck Dissection Indicator Yes 246 7.575 ± 0.03530 0.1731 13.43 ± 0.07065 0.0091
No 59 7.688 ± 0.08177 13.79 ± 0.1249
HPV p16 status Negative 16 7.730 ± 0.1301 0.26 13.63 ± 0.4052 0.1429
Positive 48 7.552 ± 0.07919 13.32 ± 0.1816