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Fig. 2 | Journal of Biomedical Science

Fig. 2

From: Effects of glucosamine against morphine-induced antinociceptive tolerance and dependence in mice

Fig. 2

Effect of glucosamine on the development of naloxone (5 mg/kg, i.p.)-induced morphine withdrawal symptoms, 2 h after last injection of morphine. Glucosamine was administered via gavage (500, 1000 and 2000 mg/kg, twice daily, for 9 days). a: Duration of tremor; b: Number of jumping; c: Number of teeth chattering; d: Number of grooming; e: Percent of animals with diarrhea. Values are expressed as means ± SEM. One way ANOVA and post hock sidak was used. *p < 0.05, ***p < 0.001 as compared to control group; #p < 0.05, and ###p < 0.001 as compared to morphine treated group

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