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Fig. 2 | Journal of Biomedical Science

Fig. 2

From: Promyelocytic leukemia zinc finger is involved in the formation of deep layer cortical neurons

Fig. 2

Plzf-deficient mice exhibit smaller cerebral cortex. a, Dorsal view of whole-mount brains at P0. For the scale size, each of the thin line indicates 1 mm, and the thick line indicates 5 mm. Quantifications of dorsal cortical surface area and cortical length shown in the lower panels. Statistical analysis performed using one-way ANOVA with appropriate post hoc tests: *p < 0.05 and **p < 0.01; Plzfwt/wt, n = 6; Plzfwt/lu, n = 9; Plzflu/lu, n = 8. b, Representative sagittal views of 9.4 T MRI sections of Plzfwt/wt and Plzflu/lu mice brain. Quantification of the volume of brain regions shown in the lower panel. Statistics performed with Student’s t test: *p < 0.05; n = 4 per genotype. Data are represented as mean ± SEM. P, postnatal day; Plzfwt/wt, wild-type; Plzfwt/lu, heterozygous; Plzflu/lu, homozygous luxoid mice; Pall, Pallium; Di, diencephalon; MB, midbrain; HB, hindbrain

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