Fig. 4
From: RETRACTED ARTICLE: Molecular mechanisms in progression of HPV-associated cervical carcinogenesis
Schematic presentation of Histone modifications by HPV E6 and E7 interaction with cellular epigenetic modifiers. HPV oncoproteins E6, E7 bind to and/or modulate the expression of histone modifying enzymes, class I Histone deacetylases (HDAC), Histone acetyltransferases (HATs), Histone lysine demethylases (KDMs) and subunits of chromatin remodeling complexes. These interactions contribute to chromatin remodelling and transcriptional regulation leading to either activation or repression of gene expression