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Fig. 2 | Journal of Biomedical Science

Fig. 2

From: HDAC6 dysfunction contributes to impaired maturation of adult neurogenesis in vivo: vital role on functional recovery after ischemic stroke

Fig. 2

Aberrant maturation of newly generated neurons in the hippocampus after MCAO. (a) Representative images of the retroviral labeled newly generated neurons born at seven days after MCAO surgery and imaged for their dendritic elaboration at 7, 14, 21 or 28 dpi. The scale bar is 25 μm. (b) Quantification of total dendritic length of individual newborn neurons obtained from 7, 14, 21 or 28 dpi. (c) Quantification of the number of dendritic branches from individual newborn neurons obtained from 7, 14, 21 or 28 dpi. Data are presented as mean ± SEM. n = 20 to 40 cells from four mice, two-tailed unpaired t-test. * p < 0.05 compared to sham-operated control

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