TY - JOUR AU - Huang, Tai-Hsiang AU - Lin, Yi-Wen AU - Huang, Chun-Ping AU - Chen, Jing-Ming AU - Hsieh, Ching-Liang PY - 2019 DA - 2019/05/11 TI - Short-term auricular electrical stimulation rapidly elevated cortical blood flow and promoted the expression of nicotinic acetylcholine receptor α4 in the 2 vessel occlusion rats model JO - Journal of Biomedical Science SP - 36 VL - 26 IS - 1 AB - Vascular dementia is the second dementing illness after Alzheimer’s disease and caused by reduced blood flow to the brain, and affects cognitive abilities. Our previous study found that auricular electrical stimulation (ES) improved motor and learning impairment, and this phenomenon related with nicotinic acetylcholine receptor (nAChR) expressed cells. However, the underlying mechanism was not clear. In the present study, we investigated the effects of auricular ES on cortical blood flow (CBF) and acetylcholine (ACh) - nAChRs expressed cells. SN - 1423-0127 UR - https://doi.org/10.1186/s12929-019-0526-9 DO - 10.1186/s12929-019-0526-9 ID - Huang2019 ER -