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Table 3 EV cargos used as diagnostic biomarkers in cancers

From: Basics and applications of tumor-derived extracellular vesicles

EV cargo Type of cargo Type of body fluid Cancer type Reference
CD63 and caveolin-1 Protein Plasma Melanoma [113]
Integrin Protein Plasma Breast cancer [39]
miR-21 miRNA Serum Esophageal squamous cell carcinoma [114]
miR-373 miRNA Serum Breast cancer [115]
miRNA signatures miRNA Serum Ovarian cancer [116]
Prostate cancer antigen 3 and TMPRSS2:ERG RNA Urine Prostate cancer [117]
Salivary transcriptomic biomarkers RNA Saliva Pancreatic cancer [118]
Specific phosphoproteins Protein Plasma Breast cancer [107]
Specific protein profile Protein Ascites Colorectal cancer [119]
Survivin Protein Plasma Prostate cancer [120]