Table 3 EV cargos used as diagnostic biomarkers in cancers
From: Basics and applications of tumor-derived extracellular vesicles
EV cargo | Type of cargo | Type of body fluid | Cancer type | Reference |
|---|---|---|---|---|
CD63 and caveolin-1 | Protein | Plasma | Melanoma | [113] |
Integrin | Protein | Plasma | Breast cancer | [39] |
miR-21 | miRNA | Serum | Esophageal squamous cell carcinoma | [114] |
miR-373 | miRNA | Serum | Breast cancer | [115] |
miRNA signatures | miRNA | Serum | Ovarian cancer | [116] |
Prostate cancer antigen 3 and TMPRSS2:ERG | RNA | Urine | Prostate cancer | [117] |
Salivary transcriptomic biomarkers | RNA | Saliva | Pancreatic cancer | [118] |
Specific phosphoproteins | Protein | Plasma | Breast cancer | [107] |
Specific protein profile | Protein | Ascites | Colorectal cancer | [119] |
Survivin | Protein | Plasma | Prostate cancer | [120] |