Table 1 Associations between CPAP expression, clinical parameters and disease-free survival/ overall survival
Clinical parameters | N | Disease-free survival (years) | Overall survival (years) | ||||||
|---|---|---|---|---|---|---|---|---|---|
Mean | 95% CI | p-value | Mean | 95% CI | p-value | ||||
CPAP expression | |||||||||
< 1.5X | 47 | 2.776 | 2.345 | 3.237 | 0.039* | 3.858 | 3.376 | 4.340 | 0.521 |
≧1.5X | 85 | 2.644 | 1.815 | 3.472 | 7.886 | 7.122 | 8.650 | ||
Gender | |||||||||
Male | 102 | 2.379 | 2.039 | 2.720 | 0.922 | 7.616 | 6.837 | 8.394 | 0.413 |
Female | 30 | 2.825 | 1.768 | 3.881 | 7.983 | 6.941 | 9.025 | ||
Age (yrs) | |||||||||
< 50 | 30 | 2.508 | 1.994 | 3.021 | 0.196 | 4.001 | 3.507 | 4.495 | 0.867 |
≧50 | 102 | 2.869 | 1.968 | 3.770 | 7.736 | 6.987 | 8.486 | ||
Liver cirrhosis | |||||||||
No | 89 | 2.042 | 1.709 | 2.376 | 0.231 | 7.855 | 7.040 | 8.671 | 0.771 |
Yes | 43 | 3.387 | 2.197 | 4.577 | 7.400 | 6.364 | 8.437 | ||
AST/GOT (U/L) | |||||||||
< 52 | 80 | 3.827 | 3.124 | 4.530 | 0.118 | 8.386 | 7.749 | 9.023 | 0.010* |
≧52 | 52 | 2.189 | 1.658 | 2.720 | 6.532 | 5.278 | 7.787 | ||
ALT/GPT (U/L) | |||||||||
< 111 | 120 | 3.083 | 2.156 | 4.010 | 0.074 | 8.030 | 7.423 | 8.637 | 0.045* |
≧111 | 12 | 1.706 | 0.822 | 2.591 | 2.648 | 1.935 | 3.361 | ||
AFP (ng/ml) | |||||||||
< 400 | 103 | 2.954 | 2.048 | 3.860 | 0.929 | 7.825 | 7.091 | 8.559 | 0.510 |
≧400 | 29 | 2.397 | 1.776 | 3.018 | 7.264 | 5.925 | 8.604 | ||
Differentiation | |||||||||
Well | 25 | 2.583 | 1.891 | 3.274 | 0.063 | 7.957 | 7.254 | 8.661 | 0.009* |
Moderate | 91 | 3.850 | 3.176 | 4.525 | 7.754 | 6.950 | 8.559 | ||
Poor | 16 | 1.207 | 0.764 | 3.900 | 3.399 | 2.227 | 4.571 | ||
Tumor size (cm) | |||||||||
< 5 | 87 | 3.536 | 2.455 | 4.617 | 0.000* | 8.346 | 7.822 | 8.870 | 0.000* |
≧5 | 45 | 1.529 | 1.086 | 1.973 | 6.007 | 4.500 | 7.513 | ||
Tumor number | |||||||||
Single | 107 | 3.034 | 2.092 | 3.976 | 0.921 | 7.764 | 7.033 | 8.495 | 0.631 |
> 1 | 25 | 2.155 | 1.572 | 2.739 | 3.227 | 2.735 | 3.718 | ||
Vascular invasion | |||||||||
Absence | 94 | 3.014 | 2.077 | 3.951 | 0.601 | 8.168 | 7.468 | 8.869 | 0.057 |
Presence | 38 | 2.110 | 1.626 | 2.593 | 6.764 | 5.532 | 7.997 | ||
AJCC Stage | |||||||||
I&II | 108 | 3.451 | 2.402 | 4.501 | 0.000* | 8.238 | 7.626 | 8.850 | 0.001* |
III | 24 | 0.910 | 0.526 | 1.295 | 3.074 | 2.281 | 3.867 | ||