|
Clinical parameters
|
N
|
Disease-free survival (years)
|
Overall survival (years)
|
|---|
|
Mean
|
95% CI
|
p-value
|
Mean
|
95% CI
|
p-value
|
|---|
|
CPAP expression
|
|
< 1.5X
|
47
|
2.776
|
2.345
|
3.237
|
0.039*
|
3.858
|
3.376
|
4.340
|
0.521
|
| ≧1.5X |
85
|
2.644
|
1.815
|
3.472
| |
7.886
|
7.122
|
8.650
| |
|
Gender
|
|
Male
|
102
|
2.379
|
2.039
|
2.720
|
0.922
|
7.616
|
6.837
|
8.394
|
0.413
|
|
Female
|
30
|
2.825
|
1.768
|
3.881
| |
7.983
|
6.941
|
9.025
| |
|
Age (yrs)
|
|
< 50
|
30
|
2.508
|
1.994
|
3.021
|
0.196
|
4.001
|
3.507
|
4.495
|
0.867
|
| ≧50 |
102
|
2.869
|
1.968
|
3.770
| |
7.736
|
6.987
|
8.486
| |
|
Liver cirrhosis
|
|
No
|
89
|
2.042
|
1.709
|
2.376
|
0.231
|
7.855
|
7.040
|
8.671
|
0.771
|
|
Yes
|
43
|
3.387
|
2.197
|
4.577
| |
7.400
|
6.364
|
8.437
| |
|
AST/GOT (U/L)
|
|
< 52
|
80
|
3.827
|
3.124
|
4.530
|
0.118
|
8.386
|
7.749
|
9.023
|
0.010*
|
| ≧52 |
52
|
2.189
|
1.658
|
2.720
| |
6.532
|
5.278
|
7.787
| |
|
ALT/GPT (U/L)
|
|
< 111
|
120
|
3.083
|
2.156
|
4.010
|
0.074
|
8.030
|
7.423
|
8.637
|
0.045*
|
| ≧111 |
12
|
1.706
|
0.822
|
2.591
| |
2.648
|
1.935
|
3.361
| |
|
AFP (ng/ml)
|
|
< 400
|
103
|
2.954
|
2.048
|
3.860
|
0.929
|
7.825
|
7.091
|
8.559
|
0.510
|
| ≧400 |
29
|
2.397
|
1.776
|
3.018
| |
7.264
|
5.925
|
8.604
| |
|
Differentiation
|
|
Well
|
25
|
2.583
|
1.891
|
3.274
|
0.063
|
7.957
|
7.254
|
8.661
|
0.009*
|
|
Moderate
|
91
|
3.850
|
3.176
|
4.525
| |
7.754
|
6.950
|
8.559
| |
|
Poor
|
16
|
1.207
|
0.764
|
3.900
| |
3.399
|
2.227
|
4.571
| |
|
Tumor size (cm)
|
|
< 5
|
87
|
3.536
|
2.455
|
4.617
|
0.000*
|
8.346
|
7.822
|
8.870
|
0.000*
|
| ≧5 |
45
|
1.529
|
1.086
|
1.973
| |
6.007
|
4.500
|
7.513
| |
|
Tumor number
|
|
Single
|
107
|
3.034
|
2.092
|
3.976
|
0.921
|
7.764
|
7.033
|
8.495
|
0.631
|
|
> 1
|
25
|
2.155
|
1.572
|
2.739
| |
3.227
|
2.735
|
3.718
| |
|
Vascular invasion
|
|
Absence
|
94
|
3.014
|
2.077
|
3.951
|
0.601
|
8.168
|
7.468
|
8.869
|
0.057
|
|
Presence
|
38
|
2.110
|
1.626
|
2.593
| |
6.764
|
5.532
|
7.997
| |
|
AJCC Stage
|
|
I&II
|
108
|
3.451
|
2.402
|
4.501
|
0.000*
|
8.238
|
7.626
|
8.850
|
0.001*
|
|
III
|
24
|
0.910
|
0.526
|
1.295
| |
3.074
|
2.281
|
3.867
| |
- *, statistically significant
