Fig. 1
In vivo tumor treatment experiments. a Schematic illustration of the treatment schedule. Groups of C57BL/6 mice (5 mice/group) were s.c. challenged with 1 × 105 TC-1 tumor cells/mouse on day 0. TC-1 tumor-bearing mice were treated with the CRT/E7 DNA vaccine and/or 3-BrPA as indicated in the timeline. b Line graph depicting the tumor volume in TC-1 tumor-bearing mice treated with the different treatment regimens. Each plot point represents the mean tumor volume of each group; the standard error is indicated by the bars. *p < 0.05. c Kaplan-Meier survival analysis of TC-1 tumor-bearing mice treated with the different treatment regimens