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Table 2 Whole genome analysis of correlation between PB1-S216G and NA mutations conferring oseltamivir resistance in human influenza A/H1N1 viruses

From: Naturally occurring mutations in PB1 affect influenza A virus replication fidelity, virulence, and adaptability

  1. Genome sets were retrieved from the Influenza Virus Database (GenBank). The NA sequences for PB1-216S viruses (blue) and PB1–216G viruses (red) were aligned and analyzed to identify NA mutations conferring oseltamivir resistance and permissive secondary mutations in NA (V241I and N369K)