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Table 2 Long-term sequelae of severe EV-A 71 infections

From: Enterovirus A71 neurologic complications and long-term sequelae

Sequelae

Possible causes

Dysphagia with nasogastric tube or gastrostomy feeding

Neuronal damage of the brainstem

Central hypoventilation with tracheostomy and ventilator support as Fig. 1 shows

Neuronal damage of the brainstem

Limb weakness/atrophy as Fig. 3 shows

Motor neuron damage

Seizure

Neuronal damage or hypoxia

Neurodevelopmental delay

Neuronal damage, younger age of onset or hypoxia

Lower cognition

Neuronal damage, younger age of onset or hypoxia

Behavioral problems, such as ADHD or oppositional symptoms

Cause to be determined

  1. ADHD attention-deficit hyperactivity disorder