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Table 2 Examination of antibacterial activity of some selected permeabilizers (phytochemicals) through agar diffusion method against certain pathogenic Gram-negative bacilli

From: Natural outer membrane permeabilizers boost antibiotic action against irradiated resistant bacteria

Permeabilizers conc. Microorganisms
Escherichia coli Acinetobacter baumannii Pseudomonas spp. Klebsiella pneumoniae Enterobacter spp.
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Gallic acid
 500 μg/ml
 600 μg/ml
 700 μg/ml +
Ellagic acid
 30 μM
 40 μM
 50 μM +
Thymol
 400 μg/ml
 500 μg/ml
 600 μg/ml + +
Chitosan
 50 ppm
 100 ppm
 250 ppm + +
EDTA
 0.1 mM
 0.5 mM
 1 mM
Sorbic acid
 2 mM
 5 mM
 10 Mm + + +
  1. (+) susceptibility (in case of disc method inhibition zone > 6 and in case of agar method inhibition zone > 10)
  2. (−) absence of susceptibility