Table 5 Effect of in vitro gamma irradiation on MIC of different antibiotics alone or combined with permeabilizers of non-beta lactamase producer bacterial isolates
From: Natural outer membrane permeabilizers boost antibiotic action against irradiated resistant bacteria
Antibiotics | MICs (mg/L) before irradiation | MICs (mg/L) after irradiation | ||||
|---|---|---|---|---|---|---|
Bacterial species | Ab-Alone | +Gallic acid | +Thymol | Alone | +Gallic acid | +Thymol |
Escherichia coli 3 | ||||||
CTX | 64 | 8 | 4 | 64 | 8 | 4 |
CFP | 64 | 16 | 16 | 128 | 32 | 32 |
E | 128 | 32 | 32 | 256 | 64 | 64 |
Acinetobacter baumannii 5 | ||||||
CTX | 32 | 8 | 8 | 32 | 8 | 8 |
CFP | 32 | 8 | 8 | 64 | 16 | 16 |
E | 64 | 32 | 16 | 128 | 64 | 32 |
Pseudomonas aeruginosa 10 | ||||||
CTX | 128 | 32 | 32 | 128 | 32 | 32 |
CFP | 128 | 32 | 32 | 256 | 64 | 64 |
E | 128 | 128 | 64 | 256 | 256 | 128 |
Enterobacter sakazakii 14 | ||||||
CTX | 8 | 2 | 4 | 8 | 2 | 4 |
CFP | 32 | 16 | 8 | 32 | 16 | 8 |
E | 64 | 16 | 16 | 64 | 16 | 16 |