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Table 5 Effect of in vitro gamma irradiation on MIC of different antibiotics alone or combined with permeabilizers of non-beta lactamase producer bacterial isolates

From: Natural outer membrane permeabilizers boost antibiotic action against irradiated resistant bacteria

Antibiotics MICs (mg/L) before irradiation MICs (mg/L) after irradiation
Bacterial species Ab-Alone +Gallic acid +Thymol Alone +Gallic acid +Thymol
Escherichia coli 3
 CTX 64 8 4 64 8 4
 CFP 64 16 16 128 32 32
 E 128 32 32 256 64 64
Acinetobacter baumannii 5
 CTX 32 8 8 32 8 8
 CFP 32 8 8 64 16 16
 E 64 32 16 128 64 32
Pseudomonas aeruginosa 10
 CTX 128 32 32 128 32 32
 CFP 128 32 32 256 64 64
 E 128 128 64 256 256 128
Enterobacter sakazakii 14
 CTX 8 2 4 8 2 4
 CFP 32 16 8 32 16 8
 E 64 16 16 64 16 16
  1. CTX Cefotaxime, CFP Cefoperazone, E Erythromycin