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Table 8 Effects of different lytic agents on the outer membrane permeability of Pseudomonas aeruginosa10 / Escherichia coli3 pretreated with permeabilizers and gamma irradiation

From: Natural outer membrane permeabilizers boost antibiotic action against irradiated resistant bacteria

Lytic agent

Conc.

Relative turbidity (%) P. aeruginosa10 / E. coli3

Control-

Gallic acid

Thymol

Radiation

Lysozyme

10 μg/mL

100 ± 1 /101 ± 1

99 ± 1/ 92 ± 1

100 ± 1/ 98 ± 0.6

100 ± 0.6/ 101 ± 2

Triton X-100

0.1%

100 ± 2 /103 ± 3

93 ± 3/86 ± 3

96 ± 1/ 90 ± 3

100 ± 1/ 101 ± 1.2

Triton X-100

1%

99 ± 3 /105 ± 0.6

81 ± 1/77 ± 2

84 ± 3/ 74 ± 4

99 ± 2/ 103 ± 3

SDS

0.1%

92 ± 1 /91 ± 2

58 ± 2/ 60 ± 1

60 ± 3/ 59 ± 3

92 ± 1/ 91 ± 5

SDS

1%

78 ± 0.6 / 80 ± 2

26 ± 1/ 42 ± 2

28 ± 2/ 50 ± 0.6

79 ± 2/ 82 ± 2

  1. The value of control cells without lytic agents was set at 100%