Skip to main content

Advertisement

Table 9 Beta lactamase assays in the presence of permeabilizer (thymol) and natural beta lactamase inhibitor (quercetin) for irradiated and non-irradiated Pseudomonas aeruginosa8 / Escherichia coli2

From: Natural outer membrane permeabilizers boost antibiotic action against irradiated resistant bacteria

Conc. control Pseudomonas aeruginosa 8 / Escherichia coli 2
aCefoperazone aCefoperazone + thymol aCefoperazone +thymol+quercetin
Before After Before After Before After
128/64 0.271/0.273 0.123 ± 0.001/ 0.148 ± 0.001 0.142 ± 0.001/ 0.161 ± 0.002 0.037 ± 0.002/ 0.049 ± 0.006 0.044 ± 0.0006/ 0.053 ± 0.002 0.196 ± 0.002/ 0.215 ± 0.001 0.211 ± 0.0006/ 0.221 ± 0.001
64 /32 0.263 /0.263 0.119 ± 0.0006/ 0.139 ± 0.002 0.133 ± 0.003/ 0.160 ± 0.001 0.030 ± 0.001/ 0.048 ± 0.001 0.040 ± 0.001/ 0.050 ± 0.0005 0.183 ± 0.003/ 0.206 ± 0.001 0.203 ± 0.001/ 0.213 ± 0.0006
32/16 0.256/0.258 0.115 ± 0.001/ 0.128 ± 0.0006 0.130 ± 0.0006/ 0.148 ± 0.002 0.02 ± 0.001/ 0.045 ± 0.001 0.039 ± 0.0006/ 0.048 ± 0.002 0.179 ± 0.001/ 0.197 ± 0.001 0.20 ± 0.006/ 0.203 ± 0.001
  1. Control = Cefoperazone antibiotic in a solution of B-CHR-TMB
  2. a Mean results of triplicate experiments