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Fig. 4 | Journal of Biomedical Science

Fig. 4

From: Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets

Fig. 4

Enhancement of SOD2 function affected TMZ-related ROS generation and apoptosis. a The MitoSox result of CD133+ cells from parental and resistant U87MG cells was presented. The mean fluorescent intensity (MFI) gated by the control was calculated into the ratio over the parental cells. The average of triplicate experiment was shown in the bar graphs. b&c Level or the expression status of caspase 3 was detected by Western blotting in (b) CD133+ U87MG-r#10 and (c) primary tumor GBM#1. SOD2 was knocked down before treatment with TMZ. (*Pā€‰<ā€‰0.05; N.S., non-significant)

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