Fig. 1

Measurement of mechanical allodynia of the mice. Behavioral response (anti-allodynia) of the mice in our chronic post-ischemic pain (CPIP) model treated with propofol (10 mg/kg, PBS & lipofundin as control), single dose. ↑ represents the injection time point. The X-axis represents the timeline (BL: basal level; 1 h, 2 h, 4 h: 1, 2, and 4 h after CPIP O-ring removal and drug injection; 1 d, 2 d, 3 d, 5 d, 7 d: 1, 2, 3, 5, and 7 days after CPIP was induced.) Values are presented as mean ± SEM, n = 5–8 per group. In the Student’s t-test, * represents P < 0.05 vs. the CPIP PBS group, and † represents P < 0.05 vs. the lipofundin group