Fig. 3

ROS of hindpaw plantar tissue. The serial changes of ROS in plantar tissue (a) and the impact of propofol (b) are presented. ROS production was measured via chemiluminescence. Values are displayed as mean ± SEM, n = 4–6 per group. a The level of ROS in CPIP were increased from 1.00 ± 0.02 (Naïve) to 1.49 ± 0.03 (2 h after CPIP) to 1.65 ± 0.09 (1 day after CPIP) then decreased to 1.10 ± 0.05 (2 days after CPIP) to 1.25 ± 0.07 (7 day after CPIP). In the Student’s t-test, § represents P < 0.05 vs. the Naïve group, ‡ represents P < 0.05 vs. the 0 h group, || represents P < 0.05 vs. the 2 h group, ¶ represents P < 0.05 vs. the Day 1 group. b The impact of propofol on ROS (2 h after CPIP) was 1.00 ± 0.08 (Naïve) to 1.54 ± 0.08 (PBS group) and decreased to 1.07 ± 0.04 (propofol group). * represents P < 0.05 vs. PBS group, † P < 0.05 vs. lipofundin group, § P < 0.05 vs. Naive group