Fig. 8From: The analgesic effect of propofol associated with the inhibition of hypoxia inducible factor and inflammasome in complex regional pain syndromeGraphic summary. In CPIP model, ROS plus HIF-1α, NALP1 and IL-1β increase and propofol administration can reduce ROS level and the expression of HIF-1α, NALP1 and IL-1β and then produced analgesia. Those effects were happened in plantar but not spinal cordBack to article page