Fig. 1

Pairwise linkage disequilibrium (LD) pattern for DBP polymorphisms in HIV-infected patients. The grey color intensity decreases with decreasing R-squared value. The location of SNPs is indicated on top. The diagonal represents a SNP and the square represents a pairwise comparison between two SNPs, indicating the magnitude of LD (D’ and r²). D’ and r² varies from 0 (absence) to 1 (complete). Abbreviations: DBP, vitamin D binding protein; SNP, single nucleotide polymorphism; LD, linkage disequilibrium; r², square of the correlation coefficient; D’; D-prime or proportion of the possible LD that was present between two SNPs