Fig. 4
From: Host immune response to anti-cancer camptothecin conjugated cyclodextrin-based polymers
The expression levels of activated cytokines and inhibitory cytokines after IT-101 treatment. (a) The expression levels of IFN-γ, TNF-α and IL-10 were detected after IT-101 treatment. (b) Higher proportion of TNF-α- and IFN-γ-secreted T cells and NK cells were observed in peripheral blood after IT-101 treatments. (c) Higher proportion of TNF-α-secreted T cells and NK cells were observed in spleen. Mouse number per group, 3 mice. The results are presented as the mean ± SD. *p < 0.05; **p < 0.0005