From: Analysis of polymorphisms, promoter methylation, and mRNA expression profile of maternal and placental P53 and P21 genes in preeclamptic and normotensive pregnant women
Haplotype rs1059234 rs1801270
PE n (%)
Control n (%)
P-value
OR (95% CI)
 CC
398 (88)
397 (87)
0.6
1.1 (0.7–1.6)
 TA
11 (2)
24 (5)
0.03
0.5 (0.2–1)
 CA
22 (5)
29 (7)
0.3
0.7 (0.4–1.3)
 TC
21 (5)
6 (1)
0.005
3.4 (1.4–8.2)