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Table 5 Haplotype analysis of maternal P21-rs1059234 and P21-rs1801270 polymorphisms and PE risk

From: Analysis of polymorphisms, promoter methylation, and mRNA expression profile of maternal and placental P53 and P21 genes in preeclamptic and normotensive pregnant women

Haplotype rs1059234 rs1801270

PE n (%)

Control n (%)

P-value

OR (95% CI)

 CC

398 (88)

397 (87)

0.6

1.1 (0.7–1.6)

 TA

11 (2)

24 (5)

0.03

0.5 (0.2–1)

 CA

22 (5)

29 (7)

0.3

0.7 (0.4–1.3)

 TC

21 (5)

6 (1)

0.005

3.4 (1.4–8.2)