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Table 6 Haplotype analysis of placental P21-rs1059234 and P21-rs1801270 polymorphisms and PE risk

From: Analysis of polymorphisms, promoter methylation, and mRNA expression profile of maternal and placental P53 and P21 genes in preeclamptic and normotensive pregnant women

Haplotype rs1059234, rs1801270

PE n (%)

Control n (%)

P-value

OR (95% CI)

 CC

188 (86)

188 (84)

0.6

1.2 (0.7–2)

 TA

10 (5)

9 (4)

0.9

1 (0.4–2.6)

 CA

7 (3)

19 (8)

0.03

0.4 (0.2–0.9)

 TC

13 (6)

8 (4)

0.2

1.9 (0.8–4.7)