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Table 10 Association between insulin-like growth factor 1 (IGF-1) expression levels and Alzheimer’s disease (AD) in brain donors with a history of traumatic brain injury (TBI)

From: The functional roles of IGF-1 variants in the susceptibility and clinical outcomes of mild traumatic brain injury

Brain region

Alzheimer’s disease

No Dementia

p-value

Samples

Mean

SD

Samples

Mean

SD

Parietal white matter (FWM)

13

0.702

0.172

20

0.722

0.227

0.776

Parietal cortex (PCx)

13

0.969

0.143

19

1.120

0.203

0.019*

Temporal cortex (TCx)

14

1.044

0.248

21

1.102

0.204

0.480

Hippocampus (HIP)

12

1.196

0.206

21

1.475

0.359

0.008**

  1. SD Standard deviation. *indicates p < 0.05, **indicates p < 0.01