Table 2 Association of insulin-like growth factor 1 (IGF-1) variants with susceptibility to mild traumatic brain injury (mTBI)
SNP | Genotype | mTBI patients (n = 176) | TWB controls (n = 1517) | Cochran-Armitage test | |
|---|---|---|---|---|---|
p-value | Bonferroni | ||||
rs35767 | GG | 75 (42.9) | 601 (41.1) | 0.964 | 1.000 |
GA | 78 (44.6) | 698 (47.8) | Â | Â | |
AA | 22 (12.6) | 162 (11.1) | Â | Â | |
rs5742612 | AA | 78 (44.8) | 752 (49.6) | 0.193 | 0.965 |
AG | 78 (44.8) | 635 (41.9) | Â | Â | |
GG | 18 (10.3) | 128 (8.4) | Â | Â | |
rs7136446 | TT | 107 (60.8) | 1049 (69.2) | 0.008** | 0.040* |
TC | 59 (33.5) | 426 (28.1) | Â | Â | |
CC | 10 (5.7) | 41 (2.7) | Â | Â | |
rs972936 | CC | 44 (25.1) | 467 (30.8) | 0.053 | 0.265 |
CT | 88 (50.3) | 754 (49.8) | Â | Â | |
TT | 43 (24.6) | 294 (19.4) | Â | Â | |
rs2072592 | CC | 88 (50.9) | 795 (52.4) | 0.818 | 1.000 |
CT | 72 (41.6) | 601 (39.6) | Â | Â | |
TT | 13 (7.5) | 120 (7.9) | Â | Â | |