Table 4 Beck Depression Inventory (BDI) scores among mild traumatic brain injury (mTBI) patients stratified by different insulin-like growth factor 1 (IGF-1) genotypes
SNP | Genotype | BDI score | OR (95% CI) | Additive modela | ||
|---|---|---|---|---|---|---|
BDI ≤9 | BDI > 9 | p-value | Bonferroni | |||
rs35767 | GG | 50 (43.1) | 23 (41.1) | 1.11 (0.70–1.78) | 0.655 | 1.000 |
GA | 52 (44.8) | 25 (44.6) | Â | Â | Â | |
AA | 14 (12.1) | 8 (14.3) | Â | Â | Â | |
rs5742612 | AA | 51 (44.0) | 25 (45.5) | 1.06 (0.65–1.73) | 0.812 | 1.000 |
AG | 54 (46.6) | 23 (41.8) | Â | Â | Â | |
GG | 11 (9.5) | 7 (12.7) | Â | Â | Â | |
rs7136446 | TT | 73 (62.4) | 32 (57.1) | 1.13 (0.67–1.90) | 0.656 | 1.000 |
TC | 37 (31.6) | 21 (37.5) | Â | Â | Â | |
CC | 7 (6.0) | 3 (5.4) | Â | Â | Â | |
rs972936 | CC | 27 (23.3) | 17 (30.4) | 0.96 (0.61–1.50) | 0.855 | 1.000 |
CT | 62 (53.4) | 23 (41.1) | Â | Â | Â | |
TT | 27 (23.3) | 16 (28.6) | Â | Â | Â | |
rs2072592 | CC | 54 (46.6) | 33 (61.1) | 0.84 (0.50–1.42) | 0.507 | 1.000 |
CT | 56 (48.3) | 14 (25.9) | Â | Â | Â | |
TT | 6 (5.2) | 7 (13.0) | Â | Â | Â | |