The functional roles of IGF-1 variants in the susceptibility and clinical outcomes of mild traumatic brain injury

Table 5 Dizziness Handicap Inventory (DHI) scores among mild traumatic brain injury (mTBI) patients stratified by different insulin-like growth factor 1 (IGF-1) genotypes

SNP	Genotype	DHI score		OR (95% CI)	Additive model^a
SNP	Genotype	DHI ≤30	DHI > 30	OR (95% CI)	p-value	Bonferroni
rs35767	GG	47 (42.3)	26 (43.3)	0.89 (0.55–1.44)	0.634	1.000
	GA	49 (44.1)	29 (48.3)
	AA	15 (13.5)	5 (8.3)
rs5742612	AA	51 (45.9)	26 (43.3)	0.91 (0.56–1.48)	0.695	1.000
	AG	46 (41.4)	31 (51.7)
	GG	14 (12.6)	3 (5.0)
rs7136446	TT	77 (69.4)	28 (45.9)	2.56 (1.49–4.41)	0.0004***	0.008**
	TC	32 (28.8)	25 (41.0)
	CC	2 (1.8)	8 (13.1)
rs972936	CC	33 (29.7)	11 (18.3)	1.85 (1.16–2.96)	0.008**	0.160
	CT	58 (52.3)	27 (45.0)
	TT	20 (18.0)	22 (36.7)
rs2072592	CC	55 (50.5)	31 (51.7)	0.91 (0.54–1.53)	0.723	1.000
	CT	45 (41.3)	26 (43.3)
	TT	9 (8.3)	3 (5.0)

^aAdjusted for sex and age. **indicates p < 0.01, ***indicates p < 0.001. OR Odds ratio, CI Confidence interval

ISSN: 1423-0127