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Table 8 Multiple neuropsychiatric symptoms of mild traumatic brain injury (mTBI) patients stratified by different insulin-like growth factor-1 (IGF-1) genotypes

From: The functional roles of IGF-1 variants in the susceptibility and clinical outcomes of mild traumatic brain injury

SNPGenotypePatients without any neuropsychiatric symptoms (n = 61)Patients with multiple neuropsychiatric symptoms (n = 18)OR (95% CI)Additive modela
p-valueBonferroni
rs35767GG27 (44.3)9 (50.0)0.79 (0.36–1.75)0.5571.000
GA26 (42.6)7 (38.9)   
AA8 (13.1)2 (11.1)   
rs5742612AA29 (47.5)9 (52.9)0.71 (0.31–1.65)0.4201.000
AG24 (39.3)7 (41.2)   
GG8 (13.1)1 (5.9)   
rs7136446TT40 (65.6)5 (27.8)3.73 (1.42–9.82)0.005**0.025*
TC19 (31.1)11 (61.1)   
CC2 (3.3)2 (11.1)   
rs972936CC15 (24.6)1 (5.6)2.58 (1.00–6.67)0.041*0.205
CT37 (60.7)11 (61.1)   
TT9 (14.8)6 (33.3)   
rs2072592CC29 (48.3)10 (58.8)0.72 (0.27–1.89)0.4931.000
CT28 (46.7)6 (35.3)   
TT3 (5.0)1 (5.9)   
  1. aAdjusted for sex and age. *indicates p < 0.05, **indicates p < 0.01. OR Odds ratio, CI Confidence interval