Table 9 Characteristics of brain donors with a history of traumatic brain injury (TBI) exposure stratified by the presence or absence of Alzheimer’s disease (AD) from GEO database (GSE104687)
|  | Alzheimer’s diseasec (n = 14) | No Dementiac (n = 26) |
|---|---|---|
Number of subjects | 14 | 26 |
Gender: Female, no. (%) | 8 (57.1) | 7 (26.9) |
Education (years) a | 14.14 ± 3.74 | 14.58 ± 3.41 |
Age at death, no. (%) | ||
 > 100 | 3 (21.4) | 1 (3.8) |
 95–99 | 0 (0) | 7 (26.9) |
 90–94 | 3 (21.4) | 5 (19.2) |
 85–89 | 4 (28.6) | 7 (26.9) |
 80–84 | 3 (21.4) | 2 (7.7) |
 75–79 | 1 (7.1) | 4 (15.4) |
Number of TBIs, no. (%) | ||
 1 | 11 (78.6) | 20 (76.9) |
 2 | 2 (14.3) | 5 (19.2) |
 3 | 1 (7.1) | 1 (3.8) |
CERAD score b | 2 [1~2.75] | 1 [1~2] |
BRAAK stage b | 5 [3.25~6] | 3 [1.25~4] |
NIA Reagan b | 2 [1~2.75] | 1 [1~2] |
APOE ε4 alleles, no. (%) | ||
 Yes | 3 (21.4) | 4 (15.4) |
 No | 10 (71.4) | 21 (80.8) |
 Unknown | 1 (7.1) | 1 (3.8) |