Skip to main content

Table 9 Characteristics of brain donors with a history of traumatic brain injury (TBI) exposure stratified by the presence or absence of Alzheimer’s disease (AD) from GEO database (GSE104687)

From: The functional roles of IGF-1 variants in the susceptibility and clinical outcomes of mild traumatic brain injury

 Alzheimer’s diseasec (n = 14)No Dementiac (n = 26)
Number of subjects1426
Gender: Female, no. (%)8 (57.1)7 (26.9)
Education (years) a14.14 ± 3.7414.58 ± 3.41
Age at death, no. (%)
 > 1003 (21.4)1 (3.8)
 95–990 (0)7 (26.9)
 90–943 (21.4)5 (19.2)
 85–894 (28.6)7 (26.9)
 80–843 (21.4)2 (7.7)
 75–791 (7.1)4 (15.4)
Number of TBIs, no. (%)
 111 (78.6)20 (76.9)
 22 (14.3)5 (19.2)
 31 (7.1)1 (3.8)
CERAD score b2 [1~2.75]1 [1~2]
BRAAK stage b5 [3.25~6]3 [1.25~4]
NIA Reagan b2 [1~2.75]1 [1~2]
APOE ε4 alleles, no. (%)
 Yes3 (21.4)4 (15.4)
 No10 (71.4)21 (80.8)
 Unknown1 (7.1)1 (3.8)
  1. amean ± standard deviation. bmedian [interquartile range]. CERAD Consortium to Establish a Registry for Alzheimer’s Disease, NIA National Institute on Aging, APOE Apolipoprotein E. cThe diagnosis was based on the DSM IV clinical diagnosis