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Fig. 6 | Journal of Biomedical Science

Fig. 6

From: Structural basis of polyethylene glycol recognition by antibody

Fig. 6

Dimer formation of 3.3-Fab in solution. The results of AUC are plotted here as curves of c(s) distribution against sedimentation coefficient. For 3.3-Fab alone the curve peaked at 3.863 S, corresponding to a molecular weight of 47.8 kDa with a friction ratio of 1.193. For 3.3-Fab and 1% PEG-550-MME it peaked at 5.167 S, suggesting a molecular weight of 90.2 kDa with a friction ratio of 1.392. These two sets of peaks indicate that the Fab formed a dimer in the presence of PEG, but existed as a monomer without PEG

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