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Fig. 1 | Journal of Biomedical Science

Fig. 1

From: Involvement of collagen XVII in pluripotency gene expression and metabolic reprogramming of lung cancer stem cells

Fig. 1

CSCs of lung cancer increase in glycolysis and oxidative phosphorylation. a, Lung cancer cells A549 cultured in spheroid medium showed increased extracellular acidification rate (ECAR) compared to cells without collagen XVII overexpression. b and c, The glucose uptake and lactate assay showed increased glucose consumption and lactate production in cells cultured with spheroid medium. d, The results of seahorse assay also showed increased OCR in cells cultured in spheroid medium. e, The mitotracker red staining showed increased mitochondria mass in cells cultured in spheroid medium. f, In ATP content assay, the data showed increased ATP production in cells cultured in spheroid medium

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