Skip to main content

Table 2 Demographic and clinical characteristics of patients with asthma and healthy controls

From: Antibody blockade of Dectin-2 suppresses house dust mite-induced Th2 cytokine production in dendritic cell- and monocyte-depleted peripheral blood mononuclear cell co-cultures from asthma patients

Determinants

Normal range

Patients with asthma

Healthy controls

Number

 

12

4

Age in years, mean (SD)

50.1 (11.4)

54.3 (8.8)

Sex, male, n (%)

7 (58.3)

2 (50.0)

Disease duration in years, medium (range)

20.0 (0.5–59)

–

Laboratory profiles

 Total eosinophil count (/μL), mean (SD)

<450.0

340.0 (236.6)

124.8 (42.6)

 Total IgE (kU/L), mean (SD)

<200.0

574.3 (1126.1)

15.5 (16.5)

 Specific anti-D. pteronyssinus IgE (kU/L), mean (SD)

<0.5

11.1 (11.1)

0.09 (0.08)

Pulmonary function test

 % of predicted FEV1, mean (SD)

>80.0

81.1 (14.9)

–

 % of predicted FEV1/FVC, mean (SD)

>70.0

69.7 (9.5)

–

Anti-asthma drugs

 Bronchodilator, n (%)

 

12 (100.0)

–

 Leukotriene antagonist, n (%)

 

2 (16.7)

–

 Corticosteroid, n (%)

 

4 (33.3)

–

 Asthma Control Test score, mean (range)a

 

18.3 (12–24)

–

  1. Abbreviation: FEV1 Forced expiratory volume in 1 s, FVC Forced vital capacity, SD Standard deviation
  2. aAsthma control test score ranges from 5 to 25, with higher scores reflecting greater asthma control