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Table 3 Correlation between clinical parameters and ratios of different CD4+ subpopulations. A comparison of different CD4+ subsets ratios was performed with total and nadir CD4 + T cell counts, CD4/CD8 ratio and viral load. Number of values (n), Spearman’s rank correlation coefficient (r), and p value are indicated

From: 7-oxo-DHEA enhances impaired M. tuberculosis-specific T cell responses during HIV-TB coinfection

Clinical parameterTh1/
FoxP3
Th1/
Tregs
Th1/
uTregs
Th1/
Th17
Th17/
FoxP3
Th17/
Tregs
Th17/
uTregs
CD4 + T cell count (cell/ml)n = 15n = 14n = 15n = 14n = 13n = 13n = 13
r = 0.59r = 0.70r = 0.55r = 0.055r = 0.57r = 0.65r = 0.24
p = 0.011p = 0.0026p = 0.018p = 0.43p = 0.024p = 0.18p = 0.44
Nadir CD4 T cell count (cell/ml)n = 15n = 14n = 15n = 14n = 14n = 14n = 14
r = 0.60r = 0.66r = 0.36r = 0.37r = 0.56r = 0.48r = 0.20
p = 0.025p = 0.018p = 0.14p = 0.15p = 0.048p = 0.16p = 0.58
CD4/CD8 T cell ration = 15n = 14n = 15n = 14n = 13n = 13n = 13
r = 0.25r = 0.49r = 0.20r = 0.23r = 0.22r = 0.33r = 0.14
p = 0.19p = 0.036p = 0.23p = 0.21p = 0.23p = 0.26p = 0.65
Viral Load (copies/ml)n = 15n = 15n = 15n = 14n = 14n = 14n = 14
r = −0.37r = −0.51r = − 0.38r = − 0.34r = − 0.25r = − 0.28r = 0.19
p = 0.087p = 0.027p = 0.081p = 0.12p = 0.19p = 0.33p = 0.52