Fig. 1
From: Translation control of Enterovirus A71 gene expression
The structure of the EV-A71 genome. The 5′ UTR of EV-A71 contains six stem-loop RNA domains (I-VI). Domain I functions in negative-strand RNA synthesis, whereas domains II–VI form an IRES element. The ORF encodes a polyprotein, which is cleaved into 11 viral proteins by viral and/or cellular proteases