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Fig. 2 | Journal of Biomedical Science

Fig. 2

From: Dopamine D3 receptor and GSK3β signaling mediate deficits in novel object recognition memory within dopamine transporter knockdown mice

Fig. 2

DAT-KD mice do not exhibit diminished GSK3α/β phosphorylation in the mPFC after novelty exposure. a Schematic representation of the experiments to evaluate DA signaling effects after novel object exposure. After 3 days of habituation, mice were allowed to explore two equal novel objects for 10 min, followed immediately by euthanization. b Levels of phosphorylation at serine 21 of GSK3α; c Levels of phosphorylation at serine 9 of GSK3β; d total amount of GSK3α and e GSK3β. Data are shown as mean ± SEM (n = 13–14 per group). *p < 0.05, **p < 0.01 compared to the WT control group

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