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Fig. 3 | Journal of Biomedical Science

Fig. 3

From: Clinical-grade cryopreserved doxorubicin-loaded platelets: role of cancer cells and platelet extracellular vesicles activation loop

Fig. 3

Drug release profiles of fresh and cryopreserved DOX-loaded PLT. Comparison of the kinetics of the release of DOX from DOX-loaded PLT (a) and cryopreserved DOX-loaded PLT (b) in PBS at pH 5.5, 6.5, and 7.4 and PAS at pH 7.4. Comparison of the kinetics of the release of DOX from DOX-loaded PLT (c) and cryopreserved DOX-loaded PLT (d) in the presence of CM, DMEM and PAS. Abbreviations: DOX: doxorubicin, PLT: platelet, PD: fresh DOX-loaded PLT, FPD: cryopreserved DOX-loaded PLT, CM: conditioned medium cultured with cancer cells, DMEM: cell culture control medium, PBS: phosphate-buffered saline, PAS: PLT additive solution

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