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Fig. 7 | Journal of Biomedical Science

Fig. 7

From: Clinical-grade cryopreserved doxorubicin-loaded platelets: role of cancer cells and platelet extracellular vesicles activation loop

Fig. 7

In vitro cytotoxicity of fresh and cryopreserved DOX-loaded PLT on cancer cell lines. (a) A549 lung cancer cells, (b) HCT 116 colon cancer cells, (c) MDA-MB-231 breast cancer cells were grown for 48 h in the presence of PD, FPD, DOX and LD. The viability was assessed with a CCK-8 assay. Cytotoxicity compared to liposomal DOX. ** p < 0.01, *** p < 0.001, **** p < 0.0001. Abbreviations: PD: fresh DOX- loaded PLT, FPD: cryopreserved DOX-loaded PLT, DOX: doxorubicin, LD: liposomal doxorubicin

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Journal of Biomedical Science

ISSN: 1423-0127