Fig. 6
From: Functions and properties of nuclear lncRNAs—from systematically mapping the interactomes of lncRNAs
Profiling R-loops (RNA-DNA hybrids). DRIP-seq and bisDRIP-seq utilize S9.6 antibodies to pull down DNA:RNA hybrids (R-loops), and the captured DNA fragments are sequenced. DRIPc-seq builds on DRIP-seq, and the captured RNA fragments are reversed transcribed and sequenced. R-ChIP captures R-loops using a standard ChIP-seq protocol to pull down R-loop/catalytic-dead RNase H complex