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Fig. 7 | Journal of Biomedical Science

Fig. 7

From: Functions and properties of nuclear lncRNAs—from systematically mapping the interactomes of lncRNAs

Fig. 7

RNA-protein droplets in cells. RNA granules are made out of protein and RNA complexes, and their formations are driven by liquid-liquid phase separation. Nucleoli, paraspeckles, Cajal bodies (CBs), histone locus bodies (HLBs) and promyelocytic leukemia (PML) bodies are RNA assemblies in the nucleus. P-bodies and stress granules are found in the cytoplasm. RNAs act as a regulatory element to control their sizes and properties. The imbalance of RNA/protein ratio in such RNA assemblies could lead to human diseases

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