Table 1 Hemagglutinin cleavage site and NAI resistance marker in wild-type viruses and CVVs
CVVs | Wild-type viruses | Pathogenicity | Modification of hemagglutinin cleavage site | Modification of NAI resistance marker (R292K) | ||
|---|---|---|---|---|---|---|
Wild type | CVVs | Wild type | CVVs | |||
NHRI-RG3 | A/Guangdong/17SF003/2016 | HPAI | PEVPKRKRTAR/GLF | PEVPKGR/GLF | K | R |
NHRI-RG4 | A/Hong Kong/125/2017 | LPAI | PEIPKGR/GLF | PEIPKGR/GLF | R | R |
NHRI-RG5 | A/Guangdong/SP440/2017 | HPAI | PEVPKRKRTAR/GLF | PEVPKGR/GLF | K | R |
NHRI-RG6 | A/Taiwan/1/2017 | HPAI | PEVPKRKRTAR/GLF | PEVPKGR/GLF | K | R |