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Table 2 LncRNAs linked to myocardial infarction

From: Expedition to the missing link: Long noncoding RNAs in cardiovascular diseases

LncRNATargetPhysiological/pathological impactMechanism involved
CAIF [50]P53Preventing detrimental autophagy and cell death of cardiomyocytesBlock p53 from activating myocardin transcription
BACE1-AS [51]BACE1Increases expression of toxic β-amyloid protein in endothelial cells and cardiomyocytesStabilize β-secretase-1 (BACE1) sense transcript to increase β-amyloid protein production
CARL [52]miR-539Regulates mitochondrial fission and apoptosisSponge miR-539 to derepress PHB2 expression
APF [53]miR-188-3pInduces adaptive cell autophagy after MISponge miR-188-3p to derepress ATG7 expression
NRF [54]miR-873Regulates programmed cardiomyocyte necrosis pathwaysActivated by p53 to sponge miR-873 and derepress RIPK1/RIPK3 expression