|
PPT1/CLN1
|
CTSD/CLN10
|
Interaction
|
SH-SY5Y human neuroblastoma cells
|
Scifo et al., 2013 [59]
|
|
CLN5
|
TPP1/CLN2
|
Interaction
|
COS-1 cells
|
Vesa et al., 2002 [77]
|
|
CLN3
|
|
CLN5
|
PPT1/CLN1
|
Interaction
|
Mouse brain extract COS-1 cells (author note: place on a separate line under "Mouse brain extract") HeLa cells (author note: place on a separate line under "COS-1 cells")
|
Lyly et al., 2009 [78]
|
|
TPP1/CLN2
| |
|
CLN3
| |
|
CLN6
|
|
CLN8
|
|
CTSD/CLN10
|
PGRN/CLN11
|
Interaction
|
HEK293T cells
|
Zhou et al., 2017; Valdez et al., 2017 [79, 80]
|
|
PPT1/CLN1
|
DNAJC5/CLN4
|
PPT1/CLN1 depalmitoylates DNAJC5/CLN4
|
PPT1/CLN1 from HEK293T cell media depalmitoylated DNAJC5/CLN4 isolated from mouse brain
|
Henderson et al., 2016 [81]
|
|
PPT1/CLN1
|
CLN5
|
PPT1/CLN1 regulates the trafficking of CLN5
|
HeLa cells
|
Lyly et al., 2009 [78]
|
|
CLN3
|
CTSD/CLN10
|
Co-localization under hypertonic conditions
|
Baby hamster kidney cells
|
Cárcel-Trullols et al., 2017 [82]
|
|
Increased expression of CLN3 under hypertonic conditions
|
CTSD/CLN10
|
Decreased activity of CTSD/CLN10
|
Baby hamster kidney cells
|
Cárcel-Trullols et al., 2017 [82]
|
|
CLN5
|
CTSD/CLN10
|
CLN5 regulates the processing of CTSD/CLN10
|
CLN5 (N320S) expressed in HeLa cells reduced the processing of CTSD/CLN10 to its enzymatically active form
|
Qureshi et al., 2018 [83]
|
|
PGRN/CLN11
|
CTSD/CLN10
|
PGRN/CLN11 increases the activity of CTSD/CLN10
|
Human PGRN and CTSD/CLN10 from bovine spleen
|
Valdez et al., 2017 [80]
|
