|
Phenotype
|
Cell Line
|
|---|
|
tpp1A−
|
cln3−
|
cln5−
|
mfsd8−
|
|---|
|
Storage body accumulation
|
Yes
|
Yes
|
Yes
|
Not tested
|
|
Aberrant cell proliferation
|
No (Yes, tpp1 knockdown)
|
Yes
|
Not tested
|
Not tested
|
|
Impaired cytokinesis
|
Not tested
|
Yes
|
Not tested
|
Not tested
|
|
Defects in osmoregulation
|
Not tested
|
Yes
|
Not tested
|
Not tested
|
|
Impaired autophagy
|
Yes
|
Not tested
|
Not tested
|
Not tested
|
|
Reduced chemotaxis
|
Not tested
|
Yes
|
Yes
|
Not tested
|
|
Aberrant secretion
|
Not tested
|
Yes
|
Not tested
|
Yes
|
|
Reduced adhesion
|
Not tested
|
Yes
|
Yes
|
Not tested
|
|
Delayed aggregation
|
Not tested
|
Yes
|
Not tested
|
Not tested
|
|
Precocious development
|
Yes
|
Yes
|
Not tested
|
Not tested
|
|
Impaired spore formation
|
Yes
|
Not tested
|
Not tested
|
Not tested
|
|
Impaired spore integrity
|
Not tested
|
Yes
|
Not tested
|
Not tested
|
