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Fig. 1 | Journal of Biomedical Science

Fig. 1

From: N6-methyladenosine methyltransferase METTL3 affects the phenotype of cerebral arteriovenous malformation via modulating Notch signaling pathway

Fig. 1

METTL3 is related to the nidus size of cerebral AVMs. a The expression levels of METTL3 in different size groups. All patients were classified into 3 groups according to maximum diameter, 0 cm < MD ≤ 2 cm, n = 5; 2 cm < MD ≤ 4 cm, n = 39; 4 cm < MD ≤ 6 cm, n = 13. b The expression levels of METTL3 in different age groups, 0 < age ≤ 20, n = 22; 20 < age ≤ 40, n = 23; 40 < age ≤ 60, n = 12 c The expression levels of METTL3 in different location groups. Eloquent, n = 25; Noneloquent, n = 32. d The expression levels of METTL3 in different Spetzler-Martin grading groups. Grade 1, n = 18; Grade 2, n = 16; Grade 3, n = 15; Grade 4, n = 8. e The expression levels of METTL3 in different hemorrhagic presentation groups. Hemorrhagic, n = 21; Non-hemorrhagic, n = 36. P values were calculated using one-way ANOVA and/or Student’s t-test. *, P < 0.05; **, P < 0.01; ***, P < 0.001

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