Skip to main content
Fig. 5 | Journal of Biomedical Science

Fig. 5

From: Activation of TGR5 protects blood brain barrier via the BRCA1/Sirt1 pathway after middle cerebral artery occlusion in rats

Fig. 5

The effect of INT777 and siRNA on TGR5 and BRCA1 expression in penumbra after middle cerebral artery occlusion (MCAO). a, b Double immunofluorescence staining showed that expression of TGR5 or BRCA1 was upregulated in the penumbra area 24 h after MCAO; INT777 treatment increased the expressions while siRNA inhibited TGR5 or BRCA1 expression. n = 6 per group. *P < 0.05 vs sham, #P < 0.05 vs MCAO+ vehicle. Bars represent mean ± SEM. Scale bar, 50 μm

Back to article page

Journal of Biomedical Science

ISSN: 1423-0127