Table 4 Multivariate analysis to assess the independent association between the four unlinked single nucleotide polymorphisms and pancreatic cancer risk
SNPs (chromosome locus, nearest gene (s)) | Cases n (%) | Controls n (%) | OR (95% CI)a | P |
|---|---|---|---|---|
rs2816938 (1q32.1, NR5A2) | ||||
 TT | 232 (83.5) | 583 (88.7) | Reference |  |
 AT+AA | 46 (16.6) | 74 (11.3) | 1.71 (1.12–2.63) | 0.01 |
rs10094872 (8q24.21, MYC) | ||||
 AA | 159 (57.2) | 429 (65.3) | Reference |  |
 TA + TT | 119 (42.8) | 228 (34.7) | 1.50 (1.10–2.04) | 0.01 |
rs9581943 (13q12.2, PDX1) | ||||
 GG | 111 (40.1) | 323 (49.1) | Reference |  |
 GA + AA | 166 (59.9) | 335 (50.9) | 1.39 (1.03–1.88) | 0.03 |
rs4885093 (13q22.1, intergenic region) | ||||
 AA | 59 (21.2) | 196 (29.8) | Reference |  |
 AG + GG | 219 (78.8) | 462 (70.2) | 1.48 (1.04–2.10) | 0.03 |